Pinal / Denovo-Pinal

Text-to-protein de novo design from Fajie Yuan's lab: a 16B-parameter model trained on 1.7B protein-text pairs that generates novel proteins from a natural-language specification via a two-stage (language→structure→sequence) process, beating ProteinDT, Chroma and ESM3. Featured in Nature News; a flagship generative science FM in the lab's protein-design line.